PT  - JOURNAL ARTICLE
AU  - HARIMOTO, NORIFUMI
AU  - ARAKI, KENICHIRO
AU  - ISHII, NORIHIRO
AU  - MURANUSHI, RYO
AU  - HOSHINO, KOUKI
AU  - HAGIWARA, KEI
AU  - TSUKAGOSHI, MARIKO
AU  - IGARASHI, TAKAMICHI
AU  - WATANABE, AKIRA
AU  - KUBO, NORIO
AU  - SHIRABE, KEN
TI  - Predictors of Postoperative Ascites After Hepatic Resection in Patients With Hepatocellular Carcinoma
AID  - 10.21873/anticanres.14437
DP  - 2020 Aug 01
TA  - Anticancer Research
PG  - 4343--4349
VI  - 40
IP  - 8
4099  - http://ar.iiarjournals.org/content/40/8/4343.short
4100  - http://ar.iiarjournals.org/content/40/8/4343.full
SO  - Anticancer Res2020 Aug 01; 40
AB  - Background: We retrospectively investigated factors predictive for ascites after hepatic resection to treat hepatocellular carcinoma (HCC). Patients and Methods: The data of 114 patients with HCC who underwent curative hepatic resection were reviewed. The patients were assigned to two groups according to the presence or not of postoperative ascites. Results: Ascites occurred in 16 patients (14.0%), and refractory ascites in four (3.5%). A MAC2-binding protein glycosylation isomer (M2BPGi) cutoff index of 1.61 [sensitivity=75.0%, specificity 67.9%, area under the curve (AUC)=0.745] and virtual touch tissue quantification (VTQ) of 2.62 (sensitivity=68.8%, specificity=89.8%, AUC=0.827) were the best cut-off values. Patients with ascites had lower serum albumin levels, higher serum creatinine levels, higher albumin-bilirubin (ALBI) grade, higher M2BPGi, higher VTQ, and longer operative time. ALBI grade 2 and both M2BPGi>1.61 and VTQ>2.62 were independent predictors of postoperative ascites. Conclusion: We demonstrated retrospectively that ALBI grade 2 and both high M2BPGi and VTQ were independent predictors of postoperative ascites in patients undergoing hepatic resection for HCC.