RT Journal Article
SR Electronic
T1 Oncological Safety of Ultrasonically Activated Surgical Devices During Gastric Cancer Surgery
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3163
OP 3167
DO 10.21873/anticanres.14298
VO 40
IS 6
A1 TAKESHI KUBOTA
A1 KATSUTOSHI SHODA
A1 SOICHIRO OGAWA
A1 TATSUYA MATSUMOTO
A1 HIDEMASA KUBO
A1 MASAYUKI YUBAKAMI
A1 TAKUMA OHASHI
A1 TOSHIYUKI KOSUGA
A1 HIROTAKA KONISHI
A1 ATSUSHI SHIOZAKI
A1 TOMOHIRO ARITA
A1 HIROKI SHIMIZU
A1 YUSUKE YAMAMOTO
A1 RYO MORIMURA
A1 HISASHI IKOMA
A1 YOSHIAKI KURIU
A1 HITOSHI FUJIWARA
A1 KAZUMA OKAMOTO
A1 EIGO OTSUJI
YR 2020
UL http://ar.iiarjournals.org/content/40/6/3163.abstract
AB Background/Aim: Ultrasonically activated surgical devices (USADs) have become indispensable instruments for gastrointestinal surgery. In this study, we investigated the oncological safety of the use of USADs. Materials and Methods: We harvested and cultivated the splashes and mist scattered from an USAD when cutting MKN45-derived cancer nodules. Seven days later, we observed viable cancer cells and the total number of cells was counted. The histopathology of the nodules cut by the USAD was also examined. Results: The existence of viable cancer cells was confirmed by ex vivo cell culture. The number of viable cancer cells was reduced by slow grasping of the USAD. The surface of cancerous tissue cut by the USAD was partially heat-denatured, however, there were some parts in which cancerous tissue was exposed on the surface. Conclusion: Surgeons should recognize the possibility that cancer cells may be scattered by USAD use.