TY - JOUR T1 - Oncological Safety of Ultrasonically Activated Surgical Devices During Gastric Cancer Surgery JF - Anticancer Research JO - Anticancer Res SP - 3163 LP - 3167 DO - 10.21873/anticanres.14298 VL - 40 IS - 6 AU - TAKESHI KUBOTA AU - KATSUTOSHI SHODA AU - SOICHIRO OGAWA AU - TATSUYA MATSUMOTO AU - HIDEMASA KUBO AU - MASAYUKI YUBAKAMI AU - TAKUMA OHASHI AU - TOSHIYUKI KOSUGA AU - HIROTAKA KONISHI AU - ATSUSHI SHIOZAKI AU - TOMOHIRO ARITA AU - HIROKI SHIMIZU AU - YUSUKE YAMAMOTO AU - RYO MORIMURA AU - HISASHI IKOMA AU - YOSHIAKI KURIU AU - HITOSHI FUJIWARA AU - KAZUMA OKAMOTO AU - EIGO OTSUJI Y1 - 2020/06/01 UR - http://ar.iiarjournals.org/content/40/6/3163.abstract N2 - Background/Aim: Ultrasonically activated surgical devices (USADs) have become indispensable instruments for gastrointestinal surgery. In this study, we investigated the oncological safety of the use of USADs. Materials and Methods: We harvested and cultivated the splashes and mist scattered from an USAD when cutting MKN45-derived cancer nodules. Seven days later, we observed viable cancer cells and the total number of cells was counted. The histopathology of the nodules cut by the USAD was also examined. Results: The existence of viable cancer cells was confirmed by ex vivo cell culture. The number of viable cancer cells was reduced by slow grasping of the USAD. The surface of cancerous tissue cut by the USAD was partially heat-denatured, however, there were some parts in which cancerous tissue was exposed on the surface. Conclusion: Surgeons should recognize the possibility that cancer cells may be scattered by USAD use. ER -