PT - JOURNAL ARTICLE AU - ENRICO FIORI AU - ANTONIETTA LAMAZZA AU - ALESSANDRO DE CESARE AU - MARCO BONONI AU - PATRIZIA VOLPINO AU - ALBERTO SCHILLACI AU - ANTONINO CAVALLARO AU - VINCENZO CANGEMI TI - Palliative Management of Malignant Rectosigmoidal Obstruction. Colostomy <em>vs.</em> Endoscopic Stenting. A Randomized Prospective Trial DP - 2004 Jan 01 TA - Anticancer Research PG - 265--268 VI - 24 IP - 1 4099 - http://ar.iiarjournals.org/content/24/1/265.short 4100 - http://ar.iiarjournals.org/content/24/1/265.full SO - Anticancer Res2004 Jan 01; 24 AB - Background: Colostomy was the palliative treatment of choice in patients with malignant unresectable rectosigmoid obstruction. Palliative endoscopic treatment of malignant rectosigmoid obstruction by endoluminal self-expanding metallic stents is nowadays a well-established procedure. Patients and Methods: Twenty-two patients, referred for treatment with diagnosis of malignant obstruction of the rectosigmoid region presenting an advanced unresectable stage, were enrolled. Patients were randomily assigned into two treatment groups (endoscopic stenting vs colostomy) according to random-number tables. The length of procedure, morbidity and mortality rate, canalization of the gastrointestinal tract, restoration of oral intake and hospital stay were assessed. Results: Endoscopic group: The median length of procedure was 36 minutes. No death was observed. None of the patients reported complications. All patients resumed bowel function within 24 hours. The restoration of oral intake was achieved one day after stent placement. The median hospital stay was 2.6 days. Colostomy group: The median length of the operation was 75.4 minutes. No mortality was reported. In 1 patient (9.1%) stoma prolapse was observed 3 days after the operation. Canalization of the gastrointestinal tract was restored when colostomy was opened (on postoperative day 3). All patients were able to resume oral feedings on postoperative day 3. The median hospital stay was 8.1 days. Conclusion: There were no statistically significant differences between the 2 groups concerning morbidity and mortality. Endoscopic stenting was significantly more effective concerning operative time, restoration of bowel function and oral intake and median hospitalization. Our results would suggest that endoscopically placed metal stents offer an effective alternative to surgical palliation in patients suffering from unresectable malignant rectosigmoid obstruction.