TY - JOUR T1 - Effect of Muscle Mass Loss After Esophagectomy on Prognosis of Oesophageal Cancer JF - Anticancer Research JO - Anticancer Res SP - 2275 LP - 2281 DO - 10.21873/anticanres.14192 VL - 40 IS - 4 AU - YOTA SHIMODA AU - TAKANOBU YAMADA AU - KEISUKE KOMORI AU - HAYATO WATANABE AU - HIROAKI OSAKABE AU - KAZUKI KANO AU - HIROHITO FUJIKAWA AU - TSUTOMU HAYASHI AU - HARUHIKO CHO AU - MANABU SHIOZAWA AU - TAKAKI YOSHIKAWA AU - SOICHIRO MORINAGA AU - YOSHIHIRO OTA AU - KENJI KATSUMATA AU - AKIHIKO TSUCHIDA AU - TAKASHI OGATA AU - TAKASHI OSHIMA Y1 - 2020/04/01 UR - http://ar.iiarjournals.org/content/40/4/2275.abstract N2 - Background/Aim: To assess the prognostic effect of muscle loss after esophagectomy and before discharge. Patients and Methods: This study retrospectively analysed 159 consecutive patients with oesophageal and gastroesophageal junction cancer who underwent esophagectomy between August 2011 and October 2015. Body composition was evaluated one week before surgery and at discharge using a bioelectrical impedance analyser. Results: The median rate of muscle mass loss (RMML) was 4.38% (range=−3.3 to +18.8). Patients with increased RMML had significantly poorer outcomes of overall survival than those with decreased RMML (p=0.015). On multivariate analysis, RMML [≥4.38, hazard ratio (HR)=2.033, 95% confidence interval (CI)=1.018-5.924, p=0.044) and pathological tumour depth (≥2, HR=3.099, 95%CI=1.339-7.172, p=0.008) were selected as independent prognostic factors. Conclusion: RMML after esophagectomy is indicative of poor prognosis in patients with esophageal cancer. ER -