RT Journal Article SR Electronic T1 High Spatial Resolution Digital Positron Emission Tomography Images With Dedicated Source-to-background Algorithm for Radiotherapy Planning JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 2567 OP 2572 DO 10.21873/anticanres.14227 VO 40 IS 5 A1 TAKAHIRO WATAKABE A1 RYO TOYA A1 TETSUO SAITO A1 TOMOHIKO MATSUYAMA A1 SHINYA SHIRAISHI A1 YUDAI KAI A1 YOSHINOBU SHIMOHIGASHI A1 NATSUO OYA YR 2020 UL http://ar.iiarjournals.org/content/40/5/2567.abstract AB Background/Aim: To evaluate the utility of high spatial resolution digital positron emission tomography images with the source-to-background ratio (SBR) algorithm for gross tumour volume (GTV) delineation. Materials and Methods: The bowl and spheres (10-37 mm) were filled with fluoro-2-deoxy-D-glucose to achieve 4-16 times background radioactivity. The images were reconstructed using three isotropic voxel sizes. The SBR and percentage threshold (TH) to SUVmax were calculated. The plots between SBR and TH were fitted using a regression equation. The contoured volumes (CVs) of the spheres were calculated by applying TH. Results: TH was 38.6+75.0/SBR for 4 mm voxel size; 39.6+37.0/SBR for 2 mm; and 38.8+35.2/SBR for 1 mm. The mean relative errors between CV and true volume for 4, 2, and 1 mm voxel sizes were 15%, 7%, and 7%, respectively. Conclusion: The present technique is useful for GTV delineation with reduced contouring error.