RT Journal Article
SR Electronic
T1 Grape Stem Extracts From Three Native Greek Vine Varieties Exhibit Strong Antioxidant and Antimutagenic Properties
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 2025
OP 2032
DO 10.21873/anticanres.14159
VO 40
IS 4
A1 ARISTIDIS S. VESKOUKIS
A1 ELENI VASSI
A1 KONSTANTINOS POULAS
A1 MANOLIS KOKKINAKIS
A1 EFTIHIA ASPRODINI
A1 SERKOS HAROUTOUNIAN
A1 DEMETRIOS KOURETAS
YR 2020
UL http://ar.iiarjournals.org/content/40/4/2025.abstract
AB Background/Aim: The winemaking procedure results in the generation of stems, a by-product that is harmful to the environment. Concomitantly, stems are rich in polyphenols and, hence, they are putatively beneficial for human health. Materials and Methods: In this study, the grape stem extracts derived from three native Greek vine varieties, namely Mavrodaphne, Muscat and Rhoditis were examined for their chemical composition and antioxidant and antimutagenic properties using a battery of in vitro biomarkers. Results: All extracts are rich in polyphenols. Moreover, they exhibit potent antioxidant and antimutagenic properties with the extract of Mavrodaphne being the strongest in reducing the DPPH• and O2−• radicals and the Fe3+ and in protecting plasmid DNA from peroxyl radical-induced oxidative modification. Conclusion: Therefore, although they are serious pollutants, grape stems contain phytochemicals with important biological properties and can be used as (ingredients of) bio-functional foods to improve certain aspects of human health.