RT Journal Article
SR Electronic
T1 Long-term Survival After Surgical Treatment of Spinal Metastasis – The Predictive Role of Sex
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 1475
OP 1479
DO 10.21873/anticanres.14091
VO 40
IS 3
A1 DENNIS KARIMI
A1 SØREN S. MORGEN
A1 SIDSEL FRUERGAARD
A1 MARTIN GEHRCHEN
A1 BENNY DAHL
YR 2020
UL http://ar.iiarjournals.org/content/40/3/1475.abstract
AB Background/Aim: An increasing number of patients undergo surgical treatment for metastatic spinal cord compression (MSCC). However, the possible role of sex as an independent predictor of long-term survival has not been studied. This study aimed to examine whether sex is associated with long-term survival after surgical treatment in patients with MSCC. Patients and Methods: A total of 110 patients were operated on for MSCC from 2005 through 2006. The relation between sex and overall survival was investigated. The follow-up period was 10 years. Results: Survival time was significantly longer for women compared to men (mean±SD: 29±5.2 vs. 14±3.6 month (p=0.01). With adjusted analysis, this difference remained statistically significant. After adjusting for specific primary tumor type and time since surgery, the hazard-ratio of 10-year survival for men compared to women was 1.47 (95% confidence intervaI=1.01-2.18, p=0.048). Conclusion: These findings indicate that sex is associated with long-term survival in patients treated for MSCC.