RT Journal Article SR Electronic T1 Evaluation of Ultrasound-guided 8-Gauge Vacuum-assisted Excision System for the Removal of US-detectable Breast Lesions JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 1719 OP 1729 DO 10.21873/anticanres.14125 VO 40 IS 3 A1 TOMMASO PERRETTA A1 FELICIANA LAMACCHIA A1 DONATELLA FERRARI A1 EMANUELA BENINATI A1 FEDERICA DI TOSTO A1 VINCENZO DE STASIO A1 ROSARIA MEUCCI A1 CARLA DI STEFANO A1 ORESTE CLAUDIO BUONOMO A1 GIANLUCA VANNI A1 CHIARA ADRIANA PISTOLESE YR 2020 UL http://ar.iiarjournals.org/content/40/3/1719.abstract AB Aim: To assess the ability of ultrasound (US)-guided vacuum-assisted breast excision (VAE) to remove Breast Imaging Reporting and Data System (BI-RADS) ≥3 breast lesions in order to analyze US features most frequently associated with complete excision. Materials and Methods: A total of 266 BI-RADS ≥3 lesions without microcalcifications underwent US-VAE. US-VAE and gold standard pathological results were compared. US features of lesions were analyzed. Results: The complete excision rate was 93.61%; the VAE agreement rate was 99.62%. Circumscribed margins, regular shape, parallel orientation, and the absence of posterior features were favorable US features associated with complete excision. Lesions completely excised were: BI-RADS 3 ≤21.10 mm and BI-RADS 4 ≤18.70 mm with one unfavorable US characteristic, and BI-RADS 4 lesions ≤13.5 mm with two unfavorable US features hindered complete removal. Two atypical ductal hyperplasias (<10 mm, one unfavorable feature) and eight ductal carcinomas in situ (≤8.7 mm, one/two unfavorable features) were completely removed. Conclusion: US-VAE is highly accurate for diagnostic purpose and, in some cases, highly successful for complete lesion excision. This success also depends on the US characteristics and size of the lesion.