PT - JOURNAL ARTICLE AU - TOMMASO PERRETTA AU - FELICIANA LAMACCHIA AU - DONATELLA FERRARI AU - EMANUELA BENINATI AU - FEDERICA DI TOSTO AU - VINCENZO DE STASIO AU - ROSARIA MEUCCI AU - CARLA DI STEFANO AU - ORESTE CLAUDIO BUONOMO AU - GIANLUCA VANNI AU - CHIARA ADRIANA PISTOLESE TI - Evaluation of Ultrasound-guided 8-Gauge Vacuum-assisted Excision System for the Removal of US-detectable Breast Lesions AID - 10.21873/anticanres.14125 DP - 2020 Mar 01 TA - Anticancer Research PG - 1719--1729 VI - 40 IP - 3 4099 - http://ar.iiarjournals.org/content/40/3/1719.short 4100 - http://ar.iiarjournals.org/content/40/3/1719.full SO - Anticancer Res2020 Mar 01; 40 AB - Aim: To assess the ability of ultrasound (US)-guided vacuum-assisted breast excision (VAE) to remove Breast Imaging Reporting and Data System (BI-RADS) ≥3 breast lesions in order to analyze US features most frequently associated with complete excision. Materials and Methods: A total of 266 BI-RADS ≥3 lesions without microcalcifications underwent US-VAE. US-VAE and gold standard pathological results were compared. US features of lesions were analyzed. Results: The complete excision rate was 93.61%; the VAE agreement rate was 99.62%. Circumscribed margins, regular shape, parallel orientation, and the absence of posterior features were favorable US features associated with complete excision. Lesions completely excised were: BI-RADS 3 ≤21.10 mm and BI-RADS 4 ≤18.70 mm with one unfavorable US characteristic, and BI-RADS 4 lesions ≤13.5 mm with two unfavorable US features hindered complete removal. Two atypical ductal hyperplasias (<10 mm, one unfavorable feature) and eight ductal carcinomas in situ (≤8.7 mm, one/two unfavorable features) were completely removed. Conclusion: US-VAE is highly accurate for diagnostic purpose and, in some cases, highly successful for complete lesion excision. This success also depends on the US characteristics and size of the lesion.