RT Journal Article
SR Electronic
T1 Aggressive Local Control With Multisite Stereotactic Body Radiation in Metastatic Ewing Sarcoma: A Literature Review and Case Report
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 951
OP 955
DO 10.21873/anticanres.14028
VO 40
IS 2
A1 AHMAD M. KARIMI
A1 SHAUNA R. CAMPBELL
A1 SHIREEN PARSAI
A1 LILYANA ANGELOV
A1 JACOB SCOTT
A1 PENG QI
A1 PETER ANDERSON
A1 SAMUEL T. CHAO
A1 ERIN S. MURPHY
YR 2020
UL http://ar.iiarjournals.org/content/40/2/951.abstract
AB Ewing sarcoma (ES) is an undifferentiated small round blue cell tumor most commonly originating in the bone of adolescents 10-20 years of age, although 30% are diagnosed in adults. The most important prognostic factor is the presence of metastatic disease. Results of the EURO-EWING 99 trial of ES patients showed that local treatment of not only the primary, but also of the sites of metastatic disease should be considered to improve event-free survival. The use of stereotactic body radiotherapy (SBRT) has been extensively reported for tumors of lung, liver, pancreas, and spine. The use of SBRT in these sites is well-accepted. Here, we report a detailed case of SBRT to multisite metastatic ES. We demonstrate the feasibility, safety, and efficacy of aggressive local control with multisite SBRT for the treatment of metastatic ES.