RT Journal Article
SR Electronic
T1 Comparison of Dose Distributions When Using Carbon Ion Radiotherapy Versus Intensity-modulated Radiotherapy for Hepatocellular Carcinoma With Macroscopic Vascular Invasion: A Retrospective Analysis
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 459
OP 464
DO 10.21873/anticanres.13974
VO 40
IS 1
A1 SHIBA, SHINTARO
A1 SHIBUYA, KEI
A1 KAWASHIMA, MOTOHIRO
A1 OKANO, NAOKO
A1 KAMINUMA, TAKUYA
A1 OKAMOTO, MASAHIKO
A1 KUBOTA, YOSHIKI
A1 NAKANO, TAKASHI
A1 OHNO, TATSUYA
YR 2020
UL http://ar.iiarjournals.org/content/40/1/459.abstract
AB Background/Aim: This study compared the dose distributions of carbon ion radiotherapy (C-ion RT) and intensity-modulated radiotherapy (IMRT) in patients with locally advanced hepatocellular carcinoma (LAHCC). Patients and Methods: A retrospective analysis was conducted in 10 consecutive patients with LAHCC who had undergone C-ion RT. The dose-volume histogram parameters of clinical plans using C-ion RT at 60 Gy and simulated plans using IMRT at 60 Gy and 50 Gy were compared. We measured the percentage of the normal liver volume that received at least 5 Gy (V5), 10 Gy (V10), 20 Gy (V20), 30 Gy (V30), 40 Gy (V40), and 50 Gy (V50). Results: The V5, V10, V20, and the mean liver dose were significantly lower in patients who received 60 Gy of C-ion RT than in those who received 50 or 60 Gy of IMRT. Conclusion: C-ion RT exhibits a better liver dose distribution than IMRT in patients with LAHCC.