TY - JOUR T1 - A Simple Clinical Instrument to Predict the Survival Probability of Breast Cancer Patients Receiving Radiotherapy for Bone Metastases JF - Anticancer Research JO - Anticancer Res SP - 367 LP - 371 DO - 10.21873/anticanres.13961 VL - 40 IS - 1 AU - STEFAN JANSSEN AU - RAPHA HAUS AU - STEVEN E. SCHILD AU - DIRK RADES Y1 - 2020/01/01 UR - http://ar.iiarjournals.org/content/40/1/367.abstract N2 - Background/Aim: Individualization of treatment may improve the outcome of patients with bone metastases from breast cancer. To support physicians when selecting individualized programs for these patients, a simple instrument for predicting survival was created. Patients and Methods: In 126 female patients with breast cancer irradiated for bone metastases, 11 characteristics were evaluated with respect to survival. Results: On Cox regression analysis, Eastern Cooperative Oncology Group performance score (0-1 vs. ≥2; p=0.032) and visceral metastases (absence vs. presence; p=0.017) were independently associated with survival and incorporated into the scoring instrument. Three prognostic groups (0, 1 or 2 points) were designated with 12-month survival rates of 38%, 57% and 91%, and 24-month survival rates of 32%, 36% and 80%, respectively (p<0.001). Conclusion: This easy-to-use scoring instrument allows physicians to estimate the lifespan of patients irradiated for bone metastases from breast cancer and can facilitate individualization of their treatment. ER -