TY - JOUR T1 - The Role of Particle Therapy in the Risk of Radio-induced Second Tumors: A Review of the Literature JF - Anticancer Research JO - Anticancer Res SP - 4613 LP - 4617 DO - 10.21873/anticanres.13641 VL - 39 IS - 9 AU - ANGELICA FACOETTI AU - AMELIA BARCELLINI AU - FRANCESCA VALVO AU - MARCO PULLIA Y1 - 2019/09/01 UR - http://ar.iiarjournals.org/content/39/9/4613.abstract N2 - One of the most important late side-effects of radiation therapy is the development of radiation-induced secondary malignancies. In the last years, this topic has significantly influenced treatment decision-making as the number of long-term cancer survivors has significantly increased with advances in treatment modalities. All efforts are being made to prevent the incidence of tumors induced by radiation. In this review article we summarize the current knowledge about treatment-related secondary cancers with a particular attention to hadrontherapy. ER -