RT Journal Article
SR Electronic
T1 Targeted Intraoperative Radiotherapy During Breast-conserving Surgery for Breast Cancer in Patients After Implant Augmentation
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 4215
OP 4218
DO 10.21873/anticanres.13582
VO 39
IS 8
A1 HANS-CHRISTIAN KOLBERG
A1 VALERY UHL
A1 SAMUELE MASSARUT
A1 DENNIS HOLMES
A1 CORNELIA KOLBERG-LIEDTKE
A1 ERICA WHINERAY KELLY
A1 GYÖRGY LÖVEY
A1 JAYANT S. VAIDYA
YR 2019
UL http://ar.iiarjournals.org/content/39/8/4215.abstract
AB Background/Aim: Targeted intraoperative radiotherapy (TARGIT IORT) is an option during breast-conserving surgery (BCS). No data have yet been published regarding the safety of TARGIT IORT with implants in situ. TARGIT IORT is an attractive option in this context because of the risk of capsular fibrosis following external beam radiotherapy (EBRT) in such patients. Patients and Methods: We are reporting a retrospective analysis of 16 patients who received TARGIT IORT during BCS for early breast cancer after previous implant-based breast augmentation. TARGIT IORT was performed using the Intrabeam™method. Results: Follow-up varied from 98 to 5 months. There were no procedure-related complications. One patient developed local recurrence after 36 months of follow-up. Among the remaining patients (15/16), no breast-cancer-related events occurred. Conclusion: This series of patients with TARGIT IORT during BCS after implant-based breast augmentation revealed no safety concerns and gives some confidence in discussing this option with selected patients.