PT - JOURNAL ARTICLE AU - HANS-CHRISTIAN KOLBERG AU - VALERY UHL AU - SAMUELE MASSARUT AU - DENNIS HOLMES AU - CORNELIA KOLBERG-LIEDTKE AU - ERICA WHINERAY KELLY AU - GYÖRGY LÖVEY AU - JAYANT S. VAIDYA TI - Targeted Intraoperative Radiotherapy During Breast-conserving Surgery for Breast Cancer in Patients After Implant Augmentation AID - 10.21873/anticanres.13582 DP - 2019 Aug 01 TA - Anticancer Research PG - 4215--4218 VI - 39 IP - 8 4099 - http://ar.iiarjournals.org/content/39/8/4215.short 4100 - http://ar.iiarjournals.org/content/39/8/4215.full SO - Anticancer Res2019 Aug 01; 39 AB - Background/Aim: Targeted intraoperative radiotherapy (TARGIT IORT) is an option during breast-conserving surgery (BCS). No data have yet been published regarding the safety of TARGIT IORT with implants in situ. TARGIT IORT is an attractive option in this context because of the risk of capsular fibrosis following external beam radiotherapy (EBRT) in such patients. Patients and Methods: We are reporting a retrospective analysis of 16 patients who received TARGIT IORT during BCS for early breast cancer after previous implant-based breast augmentation. TARGIT IORT was performed using the Intrabeam™method. Results: Follow-up varied from 98 to 5 months. There were no procedure-related complications. One patient developed local recurrence after 36 months of follow-up. Among the remaining patients (15/16), no breast-cancer-related events occurred. Conclusion: This series of patients with TARGIT IORT during BCS after implant-based breast augmentation revealed no safety concerns and gives some confidence in discussing this option with selected patients.