RT Journal Article
SR Electronic
T1 Relationship Between Preoperative Erythrocyte Sedimentation Rate and Survival After Surgery in Patients with Colorectal Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 6783
OP 6788
DO 10.21873/anticanres.13049
VO 38
IS 12
A1 SHIBUYA, NORISUKE
A1 ISHIZUKA, MITSURU
A1 TAKAGI, KAZUTOSHI
A1 IWASAKI, YOSHIMI
A1 HACHIYA, HIROYUKI
A1 AOKI, TAKU
A1 KUBOTA, KEIICHI
YR 2018
UL http://ar.iiarjournals.org/content/38/12/6783.abstract
AB Aim: To investigate the relationship between erythrocyte sedimentation rate (ESR) and postoperative survival of patients with colorectal cancer (CRC). Materials and Methods: Relationships between clinical characteristics and overall survival (OS) of patients with CRC were investigated using multivariate analysis. Receiver operating characteristics curve analysis was performed to decide the ideal cut-off values of clinical characteristics to divide patients into two groups, which were then compared using a survival curve analysis. Results: Three hundred and eleven patients with CRC undergoing surgery were enrolled. Multivariate analysis showed that ESR >40 mm/h (hazard ratio(HR)=2.601, 95% confidence interval(CI)=1.187-5.697; p=0.017) was associated with poorer OS, along with non-tubular pathology (p=0.034). Kaplan–Meier analysis revealed that patients with ESR >40 mm/h had poorer postoperative survival than those without ESR elevation (p<0.001). Conclusion: Preoperative elevation of ESR (>40 mm/h) can predict poorer postoperative survival in patients with CRC.