PT  - JOURNAL ARTICLE
AU  - SHIBUYA, NORISUKE
AU  - ISHIZUKA, MITSURU
AU  - TAKAGI, KAZUTOSHI
AU  - IWASAKI, YOSHIMI
AU  - HACHIYA, HIROYUKI
AU  - AOKI, TAKU
AU  - KUBOTA, KEIICHI
TI  - Relationship Between Preoperative Erythrocyte Sedimentation Rate and Survival After Surgery in Patients with Colorectal Cancer
AID  - 10.21873/anticanres.13049
DP  - 2018 Dec 01
TA  - Anticancer Research
PG  - 6783--6788
VI  - 38
IP  - 12
4099  - http://ar.iiarjournals.org/content/38/12/6783.short
4100  - http://ar.iiarjournals.org/content/38/12/6783.full
SO  - Anticancer Res2018 Dec 01; 38
AB  - Aim: To investigate the relationship between erythrocyte sedimentation rate (ESR) and postoperative survival of patients with colorectal cancer (CRC). Materials and Methods: Relationships between clinical characteristics and overall survival (OS) of patients with CRC were investigated using multivariate analysis. Receiver operating characteristics curve analysis was performed to decide the ideal cut-off values of clinical characteristics to divide patients into two groups, which were then compared using a survival curve analysis. Results: Three hundred and eleven patients with CRC undergoing surgery were enrolled. Multivariate analysis showed that ESR >40 mm/h (hazard ratio(HR)=2.601, 95% confidence interval(CI)=1.187-5.697; p=0.017) was associated with poorer OS, along with non-tubular pathology (p=0.034). Kaplan–Meier analysis revealed that patients with ESR >40 mm/h had poorer postoperative survival than those without ESR elevation (p<0.001). Conclusion: Preoperative elevation of ESR (>40 mm/h) can predict poorer postoperative survival in patients with CRC.