RT Journal Article
SR Electronic
T1 Comparison of Primary Tumor Size in Stage I and III Epithelial Ovarian Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 6507
OP 6511
DO 10.21873/anticanres.13015
VO 38
IS 11
A1 EDGAR PETRU
A1 CAROLA HUBER
A1 EVA SAMPL
A1 JOSEF HAAS
YR 2018
UL http://ar.iiarjournals.org/content/38/11/6507.abstract
AB Background: Two studies have found primary ovarian carcinomas in stage I disease to be larger than those in stage III. Thus, these stages may represent different tumor entities. Materials and Methods: The clinical data from 553 patients operated on between 1985 and 2012 for epithelial ovarian cancer were retrospectively analyzed. Results: Primary lesions including invasive, borderline and benign components were significantly larger in stage I compared to stage III disease (p<0.001). However, the maximum diameter of invasive components in those with stage III disease were significantly larger than in those with stage I disease (p=0.001). The size of the invasive component was not associated with the largest size of intraperitoneal metastasis. Conclusion: We were only, in part, able to reproduce the data from the two smaller published studies. The prognosis of patients with stage III disease strongly depends on the size of intraperitoneal metastases.