RT Journal Article
SR Electronic
T1 Evaluation of Periodontal Space Widening in Patients with Antiresorptive Drug-related Osteonecrosis of the Jaws (ARONJ) on Panoramic Radiographs
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5305
OP 5314
DO 10.21873/anticanres.12857
VO 38
IS 9
A1 ALEXANDRE T. ASSAF
A1 VIVIEN AMBERG
A1 RALF SMEETS
A1 JOHANNES WIKNER
A1 HENNING HANKEN
A1 JAN SEMMUSCH
A1 FLORIAN EWALD
A1 ASHKAN RASHAD
A1 REINHARD E. FRIEDRICH
YR 2018
UL http://ar.iiarjournals.org/content/38/9/5305.abstract
AB Background/Aim: The purpose of this study was to evaluate a potential widening of the periodontal space as an initial measurable imaging criterium on panoramic radiographs in patients with the diagnosis of antiresorptive drug related osteonecrosis of the jaw (ARONJ). Patients and Methods: A retrospective analysis of panoramic radiographs of 16 patients (12 females and 4 males; mean age is 70.5 years, standard deviation is 14 years) was performed, over a period of 12 months with the diagnosis of ARONJ. Panoramic radiographs of 16 healthy patients (12 females and 4 males; mean age was 70.6 years, standard deviation was 13.8 years) without diagnosis of ARONJ served as controls. All images were taken with the same device and were evaluated by two experienced maxillofacial surgeons and one dentist. Results: Compared to the control group, a mean widening of the periodontal space of 0.06 mm (confidence interval (CI)=0.05-0.17 mm) was found in the study group. However, this difference was not statistically significant. Conclusion: Although a very extensive and sophisticated interindividual comparison was performed to evaluate for slight changes of the periodontal space in patients with antiresorptive drug therapy, our results demonstrate that PDS widening is not a predictive parameter for ARONJ. Therefore, our results indicate that panoramic radiographs are not sufficient enough to allow assessment of stages and disease progress in ARONJ patients regarding to periodontal space widening.