PT - JOURNAL ARTICLE AU - HIDEYA KASHIHARA AU - MITSUO SHIMADA AU - KOZO YOSHIKAWA AU - JUN HIGASHIJIMA AU - TOMOHIKO MIYATANI AU - TAKUYA TOKUNAGA AU - MASAAKI NISHI AU - CHIE TAKASU TI - The Effect of Roux-en-Y Reconstruction on Type 2 Diabetes in the Early Postoperative Period AID - 10.21873/anticanres.12805 DP - 2018 Aug 01 TA - Anticancer Research PG - 4901--4905 VI - 38 IP - 8 4099 - http://ar.iiarjournals.org/content/38/8/4901.short 4100 - http://ar.iiarjournals.org/content/38/8/4901.full SO - Anticancer Res2018 Aug 01; 38 AB - Aim: The aim of this study was to investigate the effect of Roux-en-Y (RY) reconstruction on type 2 diabetes with gastric cancer in the early postoperative period. Patients and Methods: A total of 44 patients with gastric cancer with type 2 diabetes who underwent total gastrectomy (TG) or distal gastrectomy (DG) with Roux-en-Y reconstruction or DG with Bilroth I were enrolled. All three groups had their fasting glucose and daily insulin dose recorded preoperatively, on day 2 postoperatively (POD2) and at discharge. Results: The TG group showed low fasting glucose and daily insulin dose on POD2 compared to their preoperative state. On discharge, the fasting glucose and daily insulin dose were significantly lower in both TG and DG Roux-en-Y groups than preoperatively. Conclusion: Roux-en-Y reconstruction showed early improvement of type 2 diabetes regardless of any body weight loss. The effect of Roux-en-Y reconstruction in TG on type 2 diabetes was more remarkable than that of DG.