TY - JOUR T1 - Is FDG-PET/CT Useful for Diagnosing Pulmonary Metastasis in Patients with Soft Tissue Sarcoma? JF - Anticancer Research JO - Anticancer Res SP - 3635 LP - 3639 DO - 10.21873/anticanres.12638 VL - 38 IS - 6 AU - TOMOHITO HAGI AU - TOMOKI NAKAMURA AU - YUICHI SUGINO AU - TAKAO MATSUBARA AU - KUNIHIRO ASANUMA AU - AKIHIRO SUDO Y1 - 2018/06/01 UR - http://ar.iiarjournals.org/content/38/6/3635.abstract N2 - Background/Aim: In patients with soft tissue sarcoma (STS), distinguishing small metastatic pulmonary nodules from benign ones remains difficult. This study aimed to determine the accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in detecting pulmonary metastasis and identify factors affecting sensitivity with STS. Materials and Methods: The clinical records and chest CT and FDG-PET/CT scans of 102 patients with STS were reviewed to determine the presence of pulmonary nodules. Results: A significant relationship was observed between nodule size and maximum standardized uptake value (SUVmax). For nodules smaller than 5 mm, only 10 out of 76 metastatic pulmonary nodules exhibited FDG accumulation, showing a weak correlation between nodule size and SUVmax. Conclusion: The role of FDG-PET/CT in differentiating metastatic from benign pulmonary nodules was unsatisfactory, especially for small nodules. Careful follow-up using CT scan may still be appropriate for diagnosing pulmonary nodules smaller than 5 mm. ER -