RT Journal Article SR Electronic T1 In Vitro Anticancer Activities of B6 Vitamers: A Mini-review JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 3429 OP 3432 DO 10.21873/anticanres.13488 VO 39 IS 7 A1 TAISUKE MATSUO A1 YASUYUKI SADZUKA YR 2019 UL http://ar.iiarjournals.org/content/39/7/3429.abstract AB Vitamin B6 compounds, including pyridoxine, pyridoxal, pyridoxamine, and their phosphorylated forms, have been investigated with regard to their cancer preventive and therapeutic effects through epidemiological, in vivo, and in vitro studies. In particular, in vitro studies in cancer cells have evaluated the effects of several B6 vitamers such as pyridoxine, pyridoxal, pyridoxamine, and pyridoxal-5’-phosphate, which is a bioactive form of vitamin B6. However, the anticancer activity and concentration required to influence cancer cells vary among B6 vitamers. In this review, the various in vitro effects of vitamin B6 compounds on cancer cells are presented and discussed.