TY - JOUR T1 - Efficacy and Toxicity of Pembrolizumab in Pediatric Metastatic Recurrent Melanoma JF - Anticancer Research JO - Anticancer Res SP - 3945 LP - 3947 DO - 10.21873/anticanres.13547 VL - 39 IS - 7 AU - AGATA MARJANSKA AU - PRZEMYSLAW GALAZKA AU - MICHAL MARJANSKI AU - MARIUSZ WYSOCKI AU - JAN STYCZYNSKI Y1 - 2019/07/01 UR - http://ar.iiarjournals.org/content/39/7/3945.abstract N2 - Background/Aim: Malignant melanoma is a rare disease in the pediatric population and there are no recommendations regarding its management in children, while the current standard of care in metastatic or unresectable melanoma in adult patients includes immunotherapy (anti-CTLA-4 and anti-PD-1 antibodies). Advances in the management of adults with melanoma offer the prospect of promising therapeutic options for children. Case Report: We describe a case of a 7-year-old patient with recurrent metastatic melanoma, for whom pembrolizumab was used as an adjuvant therapy on compassionate use basis. Conclusion: Due to adverse events, the treatment was discontinued after 5 months of pembrolizumab, but with 12-months of follow-up, patient remains in complete remission. ER -