RT Journal Article
SR Electronic
T1 A New Scoring-system for Estimating Overall Survival After Radiotherapy of Recurrent Head and Neck Cancers
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 1611
OP 1613
VO 38
IS 3
A1 RADES, DIRK
A1 SEIDL, DANIEL
A1 JANSSEN, STEFAN
A1 HAKIM, SAMER G.
A1 WOLLENBERG, BARBARA
A1 BARTSCHT, TOBIAS
A1 SCHILD, STEVEN E.
YR 2018
UL http://ar.iiarjournals.org/content/38/3/1611.abstract
AB Background/Aim: Locoregional recurrences of head and neck cancers are often associated with a poor overall survival (OS). Outcomes may be improved with individualized treatments considering a patient's lifespan. A specific scoring system for estimating OS prognoses is presented. Patients and Methods: In a preceding study of these 60 patients, Eastern Cooperative Oncology Group performance score (ECOG 0-1 versus 2, p=0.002) and N-stage (N0-1 versus N2, p=0.004) were identified as independent predictors of OS. Results: In the current study, the following scoring points were assigned: ECOG performance score 2=0 points, ECOG performance score 0-1=1 point, N2=0 points, N0-1=1 point. Patient scores were 0, 1 or 2 points with 3-year OS rates of 0%, 46% and 83%, respectively (p<0.0001). On multivariable analysis, differences remained significant (p<0.0001). Conclusion: This new scoring system includes three groups of patients with significantly different OS prognoses and can assist physicians when designing individualized therapy for locoregional recurrences of head and neck cancer.