PT  - JOURNAL ARTICLE
AU  - RADES, DIRK
AU  - SEIDL, DANIEL
AU  - JANSSEN, STEFAN
AU  - HAKIM, SAMER G.
AU  - WOLLENBERG, BARBARA
AU  - BARTSCHT, TOBIAS
AU  - SCHILD, STEVEN E.
TI  - A New Scoring-system for Estimating Overall Survival After Radiotherapy of Recurrent Head and Neck Cancers
DP  - 2018 Mar 01
TA  - Anticancer Research
PG  - 1611--1613
VI  - 38
IP  - 3
4099  - http://ar.iiarjournals.org/content/38/3/1611.short
4100  - http://ar.iiarjournals.org/content/38/3/1611.full
SO  - Anticancer Res2018 Mar 01; 38
AB  - Background/Aim: Locoregional recurrences of head and neck cancers are often associated with a poor overall survival (OS). Outcomes may be improved with individualized treatments considering a patient's lifespan. A specific scoring system for estimating OS prognoses is presented. Patients and Methods: In a preceding study of these 60 patients, Eastern Cooperative Oncology Group performance score (ECOG 0-1 versus 2, p=0.002) and N-stage (N0-1 versus N2, p=0.004) were identified as independent predictors of OS. Results: In the current study, the following scoring points were assigned: ECOG performance score 2=0 points, ECOG performance score 0-1=1 point, N2=0 points, N0-1=1 point. Patient scores were 0, 1 or 2 points with 3-year OS rates of 0%, 46% and 83%, respectively (p<0.0001). On multivariable analysis, differences remained significant (p<0.0001). Conclusion: This new scoring system includes three groups of patients with significantly different OS prognoses and can assist physicians when designing individualized therapy for locoregional recurrences of head and neck cancer.