RT Journal Article SR Electronic T1 Which Primary Organ Is Most Suitable for Performing Pulmonary Metastasectomy? JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 1041 OP 1045 VO 38 IS 2 A1 FUMIHIKO HIRAI A1 IKUHIKO KINOSHITA A1 TAICHI MATSUBARA A1 NAOKI HARATAKE A1 YUKA KOUZUMA A1 SHINKICHI TAKAMORI A1 TAKAI AKAMINE A1 GOUJI TOYOKAWA A1 TETSUZO TAGAWA A1 MITSUHIRO TAKENOYAMA A1 YOSHIHIKO MAEHARA YR 2018 UL http://ar.iiarjournals.org/content/38/2/1041.abstract AB Background/Aim: The aim of this study was to assess the appropriateness of pulmonary metastasectomy (MT), with a focus on the primary organ. Patients and Methods: The pathological status of the primary organ, outcome of the MT, disease-free interval, and overall survival were assessed. Results: The primary organ was the most significant prognostic factor analyzed, with a relative risk of 4.6 (95% confidence interval: 1.69-12.56, p=0.003). Patients with colorectal carcinoma had a better survival than those with another primary organ (p=0.003). The hazard ratios by primary organ in comparison to colorectal carcinoma were 3.2 for head and neck carcinoma, 3.5 for soft tissue sarcoma, 8.3 for hepatocellular carcinoma, and 8.9 for urinary carcinoma. Conclusion: Colorectal carcinoma is associated with a greater survival benefit than cancer of other primary organs. Colorectal carcinoma cases should be more aggressively considered for MT than other primary organ cases.