PT  - JOURNAL ARTICLE
AU  - FUMIHIKO HIRAI
AU  - IKUHIKO KINOSHITA
AU  - TAICHI MATSUBARA
AU  - NAOKI HARATAKE
AU  - YUKA KOUZUMA
AU  - SHINKICHI TAKAMORI
AU  - TAKAI AKAMINE
AU  - GOUJI TOYOKAWA
AU  - TETSUZO TAGAWA
AU  - MITSUHIRO TAKENOYAMA
AU  - YOSHIHIKO MAEHARA
TI  - Which Primary Organ Is Most Suitable for Performing Pulmonary Metastasectomy?
DP  - 2018 Feb 01
TA  - Anticancer Research
PG  - 1041--1045
VI  - 38
IP  - 2
4099  - http://ar.iiarjournals.org/content/38/2/1041.short
4100  - http://ar.iiarjournals.org/content/38/2/1041.full
SO  - Anticancer Res2018 Feb 01; 38
AB  - Background/Aim: The aim of this study was to assess the appropriateness of pulmonary metastasectomy (MT), with a focus on the primary organ. Patients and Methods: The pathological status of the primary organ, outcome of the MT, disease-free interval, and overall survival were assessed. Results: The primary organ was the most significant prognostic factor analyzed, with a relative risk of 4.6 (95% confidence interval: 1.69-12.56, p=0.003). Patients with colorectal carcinoma had a better survival than those with another primary organ (p=0.003). The hazard ratios by primary organ in comparison to colorectal carcinoma were 3.2 for head and neck carcinoma, 3.5 for soft tissue sarcoma, 8.3 for hepatocellular carcinoma, and 8.9 for urinary carcinoma. Conclusion: Colorectal carcinoma is associated with a greater survival benefit than cancer of other primary organs. Colorectal carcinoma cases should be more aggressively considered for MT than other primary organ cases.