TY - JOUR T1 - Which Primary Organ Is Most Suitable for Performing Pulmonary Metastasectomy? JF - Anticancer Research JO - Anticancer Res SP - 1041 LP - 1045 VL - 38 IS - 2 AU - FUMIHIKO HIRAI AU - IKUHIKO KINOSHITA AU - TAICHI MATSUBARA AU - NAOKI HARATAKE AU - YUKA KOUZUMA AU - SHINKICHI TAKAMORI AU - TAKAI AKAMINE AU - GOUJI TOYOKAWA AU - TETSUZO TAGAWA AU - MITSUHIRO TAKENOYAMA AU - YOSHIHIKO MAEHARA Y1 - 2018/02/01 UR - http://ar.iiarjournals.org/content/38/2/1041.abstract N2 - Background/Aim: The aim of this study was to assess the appropriateness of pulmonary metastasectomy (MT), with a focus on the primary organ. Patients and Methods: The pathological status of the primary organ, outcome of the MT, disease-free interval, and overall survival were assessed. Results: The primary organ was the most significant prognostic factor analyzed, with a relative risk of 4.6 (95% confidence interval: 1.69-12.56, p=0.003). Patients with colorectal carcinoma had a better survival than those with another primary organ (p=0.003). The hazard ratios by primary organ in comparison to colorectal carcinoma were 3.2 for head and neck carcinoma, 3.5 for soft tissue sarcoma, 8.3 for hepatocellular carcinoma, and 8.9 for urinary carcinoma. Conclusion: Colorectal carcinoma is associated with a greater survival benefit than cancer of other primary organs. Colorectal carcinoma cases should be more aggressively considered for MT than other primary organ cases. ER -