PT  - JOURNAL ARTICLE
AU  - ALBERTO BAVELLONI
AU  - GIULIA RAMAZZOTTI
AU  - ALESSANDRO POLI
AU  - MANUELA PIAZZI
AU  - ENRICO FOCACCIA
AU  - WILLIAM BLALOCK
AU  - IRENE FAENZA
TI  - MiRNA-210: A Current Overview
DP  - 2017 Dec 01
TA  - Anticancer Research
PG  - 6511--6521
VI  - 37
IP  - 12
4099  - http://ar.iiarjournals.org/content/37/12/6511.short
4100  - http://ar.iiarjournals.org/content/37/12/6511.full
SO  - Anticancer Res2017 Dec 01; 37
AB  - microRNAs (miRNAs) are a group of highly conserved small non-coding RNAs that were found to enhance mRNA degradation or inhibit post-transcriptional translation. Accumulating evidence indicates that miRNAs contribute to tumorigenesis and cancer metastasis. microRNA-210 has been largely studied in the past several years and has been identified as a major miRNA induced under hypoxia. A variety of miR-210 targets have been identified pointing to its role, not only in mitochondrial metabolism, but also in angiogenesis, the DNA damage response, cell proliferation, and apoptosis. Based on earlier research findings, this review aims to provide a current overview on the involvement of miRNA-210 in biological processes and diseases.