TY - JOUR T1 - MiRNA-210: A Current Overview JF - Anticancer Research JO - Anticancer Res SP - 6511 LP - 6521 VL - 37 IS - 12 AU - ALBERTO BAVELLONI AU - GIULIA RAMAZZOTTI AU - ALESSANDRO POLI AU - MANUELA PIAZZI AU - ENRICO FOCACCIA AU - WILLIAM BLALOCK AU - IRENE FAENZA Y1 - 2017/12/01 UR - http://ar.iiarjournals.org/content/37/12/6511.abstract N2 - microRNAs (miRNAs) are a group of highly conserved small non-coding RNAs that were found to enhance mRNA degradation or inhibit post-transcriptional translation. Accumulating evidence indicates that miRNAs contribute to tumorigenesis and cancer metastasis. microRNA-210 has been largely studied in the past several years and has been identified as a major miRNA induced under hypoxia. A variety of miR-210 targets have been identified pointing to its role, not only in mitochondrial metabolism, but also in angiogenesis, the DNA damage response, cell proliferation, and apoptosis. Based on earlier research findings, this review aims to provide a current overview on the involvement of miRNA-210 in biological processes and diseases. ER -