<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">SHOJI, FUMIHIRO</style></author><author><style face="normal" font="default" size="100%">MATSUBARA, TAICHI</style></author><author><style face="normal" font="default" size="100%">KOZUMA, YUKA</style></author><author><style face="normal" font="default" size="100%">HARATAKE, NAOKI</style></author><author><style face="normal" font="default" size="100%">AKAMINE, TAKAKI</style></author><author><style face="normal" font="default" size="100%">TAKAMORI, SHINKICHI</style></author><author><style face="normal" font="default" size="100%">KATSURA, MASAKAZU</style></author><author><style face="normal" font="default" size="100%">TOYOKAWA, GOUJI</style></author><author><style face="normal" font="default" size="100%">OKAMOTO, TATSURO</style></author><author><style face="normal" font="default" size="100%">MAEHARA, YOSHIHIKO</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Relationship Between Preoperative Sarcopenia Status and Immuno-nutritional Parameters in Patients with Early-stage Non-small Cell Lung Cancer</style></title><secondary-title><style face="normal" font="default" size="100%">Anticancer Research</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2017-12-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">6997-7003</style></pages><volume><style face="normal" font="default" size="100%">37</style></volume><issue><style face="normal" font="default" size="100%">12</style></issue><abstract><style  face="normal" font="default" size="100%">Background: Although the skeletal muscle in the region of the third lumbar vertebra (L3) is generally assessed in order to judge sarcopenia, not every patient with non-small cell lung cancer (NSCLC) undergoes computed tomography including the L3 region. We hypothesized that immuno-nutritional parameters could predict the existence of sarcopenia in patients with NSCLC. Aim: The aim of this study was to retrospectively investigate the correlation between preoperative sarcopenia and immuno-nutritional parameters in patients with early-stage NSCLC. Patients and Methods: We selected 147 of patients with pathological stage I NSCLC who underwent preoperative measurement of immuno-nutritional parameters and CT including the L3 region. Results: Preoperative sarcopenia was significantly associated with female gender (p=0.0003) and poor prognosis (p=0.0322). In Kaplan–Meier analysis of overall survival (OS) by preoperative sarcopenia status, the sarcopenic group had significantly shorter OS than the non-sarcopenic group (5-year OS: 87.27% vs. 77.37%, p=0.0131, log-rank test). In multivariate analysis, the preoperative sarcopenia status (hazard ratio=5.138; 95% confidence interval=2.305-11.676; p&lt;0.0001) was an independent prognostic factor. Preoperative sarcopenia status was significantly related to controlling nutritional status score (p=0.0071) and Geriatric Nutritional Risk Index (GNRI) (p&lt;0.0001). Spearman's correlation test showed good significant correlation between preoperative sarcopenia status and GNRI (r=0.348, p&lt;0.0001). Conclusion: The preoperative GNRI is a simple and useful predictor for existence of preoperative sarcopenia which was associated with poor outcome in patients with early-stage NSCLC.</style></abstract></record></records></xml>