RT Journal Article SR Electronic T1 Clinical Significance of C-Reactive Protein-to-Albumin Ratio with Rectal Cancer Patient Undergoing Chemoradiotherapy Followed by Surgery JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5797 OP 5804 VO 37 IS 10 A1 SHOZO IDE A1 YUJI TOIYAMA A1 YOSHINAGA OKUGAWA A1 SATOSHI OKI A1 HIROMI YASUDA A1 HIROYUKI FUJIKAWA A1 SHIGEYUKI YOSHIYAMA A1 JUNITIRO HIRO A1 MINAKO KOBAYASHI A1 MASAKI OHI A1 TOSHIMITSU ARAKI A1 MASATO KUSUNOKI YR 2017 UL http://ar.iiarjournals.org/content/37/10/5797.abstract AB Background/Aim: This study was designed to evaluate the clinical significance of the C-reactive protein-to-albumin ratio (CAR) in patients with rectal cancer undergoing preoperative chemoradiotherapy (CRT) followed by surgery. Patients and Methods: This retrospective study evaluated the correlation between CAR and prognosis in 115 patients with locally advanced rectal cancer. We also carried out subgroup analyses limited to patients with low modified Glasgow prognosis score (mGPS) (score 0) or pathological TNM stage I-II [ypN(−)]. Results: CAR exhibited significant relationships with sex, tumor invasion, recurrence, serum carcinoembryonic antigen, and mGPS. Elevated CAR was an independent prognostic factor for overall survival (OS) and disease-free survival (DFS) among all patients. Elevated CAR also predicted poor OS and DFS in patients with pathological TNM stage I-II [ypN(−)] and low mGPS score. Conclusion: CAR is a promising predictor of survival and recurrence in patients with rectal cancer treated by CRT.