TY - JOUR T1 - Microsatellite Status of Primary Colorectal Cancer Predicts the Incidence of Postoperative Colorectal Neoplasms JF - Anticancer Research JO - Anticancer Res SP - 5785 LP - 5790 VL - 37 IS - 10 AU - AKI TAKIYAMA AU - TOSHIAKI TANAKA AU - YOKO YAMAMOTO AU - KEISUKE HATA AU - SOICHIRO ISHIHARA AU - HIROAKI NOZAWA AU - KAZUSHIGE KAWAI AU - TOMOMICHI KIYOMATSU AU - TAKESHI NISHIKAWA AU - KENSUKE OTANI AU - KAZUHITO SASAKI AU - TOSHIAKI WATANABE Y1 - 2017/10/01 UR - http://ar.iiarjournals.org/content/37/10/5785.abstract N2 - Background/Aim: Few studies have evaluated the risk of postoperative colorectal neoplasms stratified by the nature of primary colorectal cancer (CRC). In this study, we revealed it on the basis of the microsatellite (MS) status of primary CRC. Materials and Methods: We retrospectively reviewed 338 patients with CRC and calculated the risk of neoplasms during postoperative surveillance colonoscopy in association with the MS status of primary CRC. A propensity score method was applied. Results: We identified a higher incidence of metachronous rectal neoplasms after the resection of MS stable CRC than MS instable CRC (adjusted HR 5.74, p=0.04). We also observed a higher incidence of colorectal tubular adenoma in patients with MSS CRC (adjusted hazard ratio 7.09, p<0.01) and a higher incidence of postoperative tubulovillous/villous adenoma in patients with MS instable CRC (adjusted HR=8.50, p=0.03). Conclusion: The MS status of primary colorectal cancer influenced the risk of postoperative colorectal neoplasms. ER -