@article {DELGADO5101, author = {ALBERTO FALK DELGADO and ANNA FALK DELGADO}, title = {Inconsistent Reporting Between Meta-analysis Protocol and Publication {\textendash} A Cross-Sectional Study}, volume = {37}, number = {9}, pages = {5101--5107}, year = {2017}, publisher = {International Institute of Anticancer Research}, abstract = {Background: Inconsistent reporting in published meta-analyses compared to registered protocol are poorly understood. The aim of the study was to assess inconsistencies between registered protocols and published reports among oncology drug meta-analyses. Materials and Methods: A cross-sectional study was performed including oncology drug meta-analyses published between January 1st and November 14th 2016 with a published protocol. Two investigators extracted data on: selection criteria, outcome(s) and statistical plan in protocol and manuscript, plus self-acknowledgement of inconsistent reporting between protocol and publication. Results: Protocol registration was present in 19\% (23/119) of all oncology drug meta-analyses. In meta-analyses with protocol (n=23), 70\% (16/23) had issues with inconsistent reporting between protocol and published report concerning; inclusion criteria, comparator group, intervention, outcome (PICO) or statistical analysis. Self-acknowledgement of changes between protocol and publication was found in 50\% (8/16). Conclusion: In meta-analyses with protocol, discrepancies between registered protocols and publications are frequent.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/37/9/5101}, eprint = {https://ar.iiarjournals.org/content/37/9/5101.full.pdf}, journal = {Anticancer Research} }