TY - JOUR T1 - Long-term Clinical Results of Concurrent Chemoradiotherapy for Patients with Cervical Esophageal Squamous Cell Carcinoma JF - Anticancer Research JO - Anticancer Res SP - 5039 LP - 5044 VL - 37 IS - 9 AU - ATSUHIRO KUMABE AU - SADATOMO ZENDA AU - ATSUSHI MOTEGI AU - MASAKATSU ONOZAWA AU - NAOKI NAKAMURA AU - TAKASHI KOJIMA AU - HIROYUKI DAIKO AU - NAOYUKI SHIGEMATSU AU - TETSUO AKIMOTO Y1 - 2017/09/01 UR - http://ar.iiarjournals.org/content/37/9/5039.abstract N2 - Background/Aim: We assessed the efficacy and toxicity of concurrent chemoradiotherapy (CCRT) in patients with squamous cell carcinoma of the cervical esophagus. Patients and Methods: We retrospectively analyzed 37 patients treated with definitive CCRT. The patients received radiotherapy at a fraction dose of 2 Gy (total; 60 or 70 Gy) and concurrent chemotherapy. Adjuvant chemotherapy consisted of 1 to 2 cycles of 5-fluorouracil plus cisplatin or nedaplatin. Results: The median follow-up was 119.0 months, the 10-year overall survival, progression-free survival and laryngectomy-free survival rates were 35.6, 19.9 and 30.2% respectively. In the univariate analysis, T stage (T4 vs. T1-3) was the only prognostic factor for PFS. The most common acute toxicity was leukocytopenia (Grade 3; 27%). As for late toxicities, 4 patients (11%) developed Grade 2 or 3 esophageal strictures. Conclusion: The results of this study demonstrated that CCRT yielded satisfactory clinical outcomes with acceptable toxicities. ER -