RT Journal Article
SR Electronic
T1 Study on the Validity of Pancreaticoduodenectomy in the Elderly
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5309
OP 5316
VO 37
IS 9
A1 YASURO FUTAGAWA
A1 MASARU KANEHIRA
A1 KENEI FURUKAWA
A1 HIROAKI KITAMURA
A1 SEIYA YOSHIDA
A1 TERUYUKI USUBA
A1 TAKEYUKI MISAWA
A1 YUICHI ISHIDA
A1 TOMOYOSHI OKAMOTO
A1 KATSUHIKO YANAGA
YR 2017
UL http://ar.iiarjournals.org/content/37/9/5309.abstract
AB Aim: Pancreaticoduodenectomy (PD) is still the only curative treatment for periampullary cancer. Confirming the outcomes of PD in elderly patients is important as the aging population continues to grow. Patients and Methods: We analyzed 340 patients with periampullary cancer who underwent PD, dividing them into three groups by age: group A: aged 64 years or younger, n=115; group B: 65-74 years, n=144; and group C: 75 years or older, n=81. Results: Group C had a significantly higher 60-day mortality of 6.3% (p=0.04), the lowest 5-year overall survival rate of 9.9% (p=0.02), and there was no impact of staging of the Union for International Cancer Control classification on overall survival of patients with pancreatic cancer. Independent prognostic factors of group C in the multivariate analysis were pancreatic cancer and reoperation. Conclusion: For elderly patients aged 75 years or over, caution should be exercised in selecting PD for patients with pancreatic cancer.