RT Journal Article SR Electronic T1 Lower Body Lymphedema in Patients with Gynecologic Cancer JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4005 OP 4015 VO 37 IS 8 A1 NICOLETTA BIGLIA A1 VALENTINA ZANFAGNIN A1 ALBERTO DANIELE A1 ELISABETTA ROBBA A1 VALENTINA E. BOUNOUS YR 2017 UL http://ar.iiarjournals.org/content/37/8/4005.abstract AB Lower body lymphedema is a chronic condition and a significant cause of morbidity following treatment of gynecologic cancer that strongly impacts patients' quality of life (QoL). Most studies on secondary lymphedema have been performed on the upper limb after breast cancer treatment and much less is known about lower body lymphedema after gynecologic malignancies. This review focuses on secondary lymphedema due to gynecologic cancer treatment, analyzing its incidence in the different types of gynecologic cancer, diagnosis, risk factors, impact on QoL and treatment. A systematic search of Medline has been performed to track the studies evaluating lower body lymphedema after treatment for endometrial, ovarian, cervical and vulvar cancer. Unfortunately, there is no consensus about a uniform evaluation and, as a consequence, the reported incidence is broadly different among the studies. Standardization in lymphedema evaluation is required to better compare the outcome of different types of treatment.