PT  - JOURNAL ARTICLE
AU  - GABRIEL LIBERALE
AU  - CÉLINE LECOCQ
AU  - CAMILO GARCIA
AU  - KRISTOF MUYLLE
AU  - ANGÉLIQUE COVAS
AU  - AMÉLIE DELEPORTE
AU  - ALAIN HENDLISZ
AU  - FIKRI BOUAZZA
AU  - ISSAM EL NAKADI
AU  - PATRICK FLAMEN
TI  - Accuracy of FDG-PET/CT in Colorectal Peritoneal Carcinomatosis: Potential Tool for Evaluation of Chemotherapeutic Response
DP  - 2017 Feb 01
TA  - Anticancer Research
PG  - 929--934
VI  - 37
IP  - 2
4099  - http://ar.iiarjournals.org/content/37/2/929.short
4100  - http://ar.iiarjournals.org/content/37/2/929.full
SO  - Anticancer Res2017 Feb 01; 37
AB  - Background/Aim: Neoadjuvant chemotherapy may be administered to patients with peritoneal carcinomatosis (PC) of colorectal cancer (CRC) origin. This study evaluated the performance of 18fluorodeoxyglucose positron-emission tomography (FDG-PET)/computed tomography (CT) in detection of PC from CRC and correlated the most metabolically active quadrant with the most affected peritoneal area determined during surgery. Patients and Methods: This retrospective study compared the performance of FDG-PET/CT for PC diagnosis in 26 patients with CRC with histopathologically-confirmed PC with a control group of 26 patients. An FDG-PET/CT score established for each patient diagnosed with PC was compared with the peritoneal cancer index (PCI) performed during surgery. Results: The sensitivity and specificity of FDG-PET/CT for PC detection were 85% (22/26) and 88% (23/26), respectively. The most scored quadrant by FDG-PET/CT corresponded to the most scored quadrant at surgery in 77.3%. Conclusion: FDG-PET/CT may represent a useful tool for evaluating response to neoadjuvant chemotherapy in patients with PC of CRC origin.