RT Journal Article
SR Electronic
T1 Surgical Resection for Pulmonary Metastasis from Pancreatic and Biliary Tract Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 1413
OP 1416
VO 37
IS 3
A1 TETSUZO TAGAWA
A1 KENSAKU ITO
A1 KENGO FUKUZAWA
A1 TATSURO OKAMOTO
A1 ATSURO YOSHIMURA
A1 TAKAHIDE KAWASAKI
A1 TAKASHI MASUDA
A1 KENTARO IWAKI
A1 TAKAHIRO TERASHI
A1 MASAHIRO OKAMOTO
A1 AKIO SHIROMIZU
A1 AKIRA MOTOHIRO
A1 YOSHIHIKO MAEHARA
YR 2017
UL http://ar.iiarjournals.org/content/37/3/1413.abstract
AB Aim: To determine the efficacy of pulmonary metastasectomy for pancreatic and biliary tract cancer. Patients and Methods: Ten patients who underwent therapeutic pulmonary metastasectomy after resection for pancreatic and biliary tract cancer at our Institution from 2006 to 2016 were retrospectively evaluated. Results: The primary site was the pancreas in four patients and biliary tract in six. Nine patients had single metastasis, and one patient had bilateral multiple metastases. The median time from surgery for the primary tumor to pulmonary resection was 23.3 months (range= 0-47.1 months). One patient underwent lobectomy, while nine patients underwent partial resection. One patient had incomplete resection due to pleural dissemination. There were no postoperative mortalities or major morbidities. The mean follow-up period was 26.0 months. The median survival time was 38.5 months, and the estimated 5-year overall survival was 38.9% after pulmonary resection. Five patients had recurrent disease after pulmonary resection, with a median recurrence-free interval of 6.0 months. One patient underwent second pulmonary resection for a solitary lung recurrence. Conclusion: Despite the poor prognoses of these cancer types, pulmonary metastasectomy can significantly prolong survival in selected patients with pancreatic and biliary tract cancer.