PT - JOURNAL ARTICLE AU - KATSUYUKI SHIRAI AU - JUN-ICHI SAITOH AU - ATSUSHI MUSHA AU - TAKANORI ABE AU - DAIJIRO KOBAYASHI AU - YOSUKE TAKAKUSAGI AU - YUKIHIRO TAKAYSU AU - MASATO SHINO AU - MINORU TOYODA AU - KATSUMASA TAKAHASHI AU - KAZUAKI CHIKAMATSU AU - TATSUYA OHNO AU - TAKASHI NAKANO TI - Clinical Outcomes of Definitive and Postoperative Radiotherapy for Stage I-IVB Hypopharyngeal Cancer DP - 2016 Dec 01 TA - Anticancer Research PG - 6571--6578 VI - 36 IP - 12 4099 - http://ar.iiarjournals.org/content/36/12/6571.short 4100 - http://ar.iiarjournals.org/content/36/12/6571.full SO - Anticancer Res2016 Dec 01; 36 AB - Background: Hypopharyngeal cancer is relatively rare disease and continues to have a poor prognosis. This study analyzed the efficacy and safety of radiotherapy for stage I-IVB hypopharyngeal cancer. Patients and Methods: Between 2000 and 2015, 72 patients were treated with definitive radiotherapy and 29 patients with stage IVA were treated with postoperative radiotherapy. Results: With definitive radiotherapy, the 3-year locoregional control rates for stage I-II, III, IVA, and IVB disease were 89%, 74%, 51% and 0%, respectively. The 3-year overall survival rates for patients with stage I-II, III, IVA and IVB disease were 84%, 89%, 55% and 15%, respectively. In patients with stage IVA disease treated with postoperative radiotherapy, 3-year locoregional control and overall survival rates were 83% and 75%, respectively, which were significantly better than those treated with definitive radiotherapy. Conclusion: Definitive radiotherapy was effective for stage I-III disease. Surgery and postoperative radiotherapy improved the survival rate of patients with stage IVA hypopharyngeal cancer.