RT Journal Article
SR Electronic
T1 Could Patients Older than 75 Years Benefit from a Systematic Breast Cancer Screening Program?
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 903
OP 907
VO 37
IS 2
A1 ILENKO, ANNA
A1 SERGENT, FABRICE
A1 MERCUZOT, ANTONIN
A1 ZITOUN, MICKAËL
A1 CHAUFFERT, BRUNO
A1 FOULON, ARTHUR
A1 GONDRY, JEAN
A1 CHEVREAU, JULIEN
YR 2017
UL http://ar.iiarjournals.org/content/37/2/903.abstract
AB Background/Aim: To assess prognosis of women aged 75 and older according to breast cancer (BC) diagnosis circumstances. Patients and Methods: A retrospective cohort study was conducted in the Amiens, France, regional oncologic referral center between 2005 and 2015. Two groups were formed depending on whether the patients followed clinical manifestations (CM) or a prescribed systematic mammography (SM). Results: Three hundred and ninenty-three patients were selected. CM and SM represented 72% and 14.5% of BC diagnosis circumstances, respectively. In the SM group statistically significant differences included: earlier stage cancer diagnosis (tumor stages 0 and 1 accounted for 6.3% and 61.4% of cases, respectively), less lymph node invasions (35.7% and 8.8%) and metastases (19.1% and 0%), more frequent possibility of conservative surgery (25.6% and 74.5%), improved global and disease-free survival rates (by 14.2 and 18.4 months). Conclusion: Screening seems to improve prognosis of older BC patients; this constitutes a strong argument for reconsidering age limits of national BC screening programs.