TY - JOUR T1 - Inflammation-based Prognostic Score in Patients with Living Donor Liver Transplantation for Hepatocellular Carcinoma JF - Anticancer Research JO - Anticancer Res SP - 5537 LP - 5542 VL - 36 IS - 10 AU - NORIFUMI HARIMOTO AU - TOMOHARU YOSHIZUMI AU - TOMONARI SHIMAGAKI AU - AKIHISA NAGATSU AU - TAKASHI MOTOMURA AU - NOBORU HARADA AU - HIROHISA OKABE AU - SHINJI ITOH AU - TORU IKEGAMI AU - HIDEAKI UCHIYAMA AU - YUJI SOEJIMA AU - YOSHIHIKO MAEHARA Y1 - 2016/10/01 UR - http://ar.iiarjournals.org/content/36/10/5537.abstract N2 - Background: Inflammation-besed prognostic score including neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), modified Glasgow prognostic score (mGPS) and prognostic nutritional index (PNI) have prognostic value in various malignancies. Patients and Methods: We retrospectively investigated their prognostic value in 213 patients with living donor liver transplantation (LDLT) for hepatocellular carcinoma (HCC). Disease-free survival (DFS) following LDLT was calculated; NLR, PLR, PNI and mGPS values in patients with and without recurrence were compared. Risk factors for HCC recurrence were identified by univariate and multivariate analyses. Results: Both NLR and PLR were significantly increased in patients with recurrence. Multivariate analysis showed that des-gamma-carboxy prothrombin (DCP) ≥300 mAU/ml, NLR ≥2.66, <3 months between last HCC treatment to LDLT were independent predictors of DFS. Conclusion: Preoperative NLR was an independent, inflammation-based prognostic marker of DFS and was predictive of recurrence following LDLT. ER -