@article {NONAKA5419, author = {TAKASHI NONAKA and AKIKO FUKUDA and KYOICHIRO MAEKAWA and SHIGEKI NAGAYOSHI and TAKAYUKI TOKUNAGA and MITSUHISA TAKATSUKI and TOMOO KITAJIMA and KEN TANIGUCHI and HIKARU FUJIOKA}, title = {Clinical and Oncological Outcomes of Laparoscopic Versus Open Surgery for Advanced Rectal Cancer}, volume = {36}, number = {10}, pages = {5419--5424}, year = {2016}, publisher = {International Institute of Anticancer Research}, abstract = {Aim: To compare the clinical and oncological outcomes of laparoscopic and open approaches in patients with advanced rectal cancer. Patients and Methods: In this study, 78 patients who underwent surgery for advanced middle and lower rectal cancer (pStage II - III) were divided into two groups according to type of surgical approach: laparoscopic surgery (LS group; n=40) and open surgery (OS group: n=38). The clinical outcomes and oncological outcomes were compared between the two groups. Results: The operation time was comparable, whereas operative blood loss and complication rates were significantly less in the LS group compared to the OS group. Cancer-specific survival (CSS) and local recurrence-free survival (LRFS) were similar in the two groups. Disease-free survival (DFS) was better in the LS group than in the OS group. Conclusion: LS for advanced rectal cancer was safe and not inferior to OS in clinical and oncological outcomes.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/36/10/5419}, eprint = {https://ar.iiarjournals.org/content/36/10/5419.full.pdf}, journal = {Anticancer Research} }