RT Journal Article
SR Electronic
T1 Non-epithelial Ovarian Cancer: Elucidating Uncommon Gynaecological Malignancies
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5031
OP 5042
VO 36
IS 10
A1 BOUSSIOS, STERGIOS
A1 ZARKAVELIS, GEORGE
A1 SERAJ, ESMERALDA
A1 ZERDES, IOANNIS
A1 TATSI, KONSTANTINA
A1 PENTHEROUDAKIS, GEORGE
YR 2016
UL http://ar.iiarjournals.org/content/36/10/5031.abstract
AB Non-epithelial ovarian cancers (NEOC) are a group of fascinating but uncommon malignancies which can be extremely challenging to treat. Collectively, these tumours only represent 10-15% of all ovarian cancers and occur in all age groups from childhood to old age. This broad term includes diverse tumours of germ cell origin, sex cord-stromal cell origin, as well as extremely rare types of ovarian cancer, such as small-cell carcinomas and sarcomas, each of which require specialist management. It is imperative that these rare tumours are managed with accurate diagnosis, staging and treatment in order to optimize patient outcomes. The aetiology and molecular origins of each sub-group of NEOC remain poorly understood and international cooperation to facilitate high quality translational research is needed. This review summarizes the published literature on the incidence, clinical presentation, pathology, therapeutic interventions, survival and prognostic factors of each sub-type of NEOC.