@article {KITAGAWA4063, author = {HIROYUKI KITAGAWA and TOMOAKI YATABE and TSUTOMU NAMIKAWA and MASAYA MUNEKAGE and KAZUHIRO HANAZAKI}, title = {Postoperative Closed-loop Glycemic Control Using an Artificial Pancreas in Patients After Esophagectomy}, volume = {36}, number = {8}, pages = {4063--4067}, year = {2016}, publisher = {International Institute of Anticancer Research}, abstract = {Aim: This study investigated the efficacy of an artificial pancreas in managing postoperative glycemic levels for patients after esophagectomy. Patients and Methods: We reviewed 107 patients with esophageal cancer who underwent esophagectomy, and had postoperative glucose management using the artificial pancreas. The target blood glucose level (TBGL) range was 90-140 mg/dl. Achievement rate of TBGL, total insulin use, number of severe hypoglycemic (\<40 mg/dl) events, surgical complications and length of hospitalization (LOH) were evaluated. Results: Mean achievement rate of TBGL was 78.2\%. Mean total insulin use was 47.9 units. Mean blood glucose level was 136.3 mg/dl (mean SD=20.7). The incidences of pneumonia, anastomotic leak, and surgical site infection were 11.2\%, 12.1\%, 23.4\%, respectively. The mean LOH was 29.6 days. No patient developed severe hypoglycemia. Conclusion: Artificial pancreatic systems could minimize blood glucose variability and prevent severe hypoglycemic events for patients after esophagectomy.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/36/8/4063}, eprint = {https://ar.iiarjournals.org/content/36/8/4063.full.pdf}, journal = {Anticancer Research} }