RT Journal Article
SR Electronic
T1 Effective Treatment of Pleural Epitheloid Hemangio-endothelioma with Pazopanib: A Case Report
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 351
OP 354
VO 36
IS 1
A1 DENIS SCHALLIER
A1 BEREND-JAN BERENDES
A1 PIERRE LEFESVRE
A1 HENDRIK EVERAERT
YR 2016
UL http://ar.iiarjournals.org/content/36/1/351.abstract
AB A patient with a pleural epitheloid hemangio-endothelioma (EHE) who failed to respond to six cycles of initial chemotherapy with iphosphamide and epirubicine was treated with pazopanib in second-line. A significant subjective and objective metabolic response on 18F-fluoro-deoxyglucose positron-emission tomography-computed tomography was noted. Based on this observation, the role of vasculoendothelial growth factor receptor inhibitors such as pazopanib (or other tyrosine kinase inhibitors), in the treatment of pleural EHE should be established through prospective collaborative studies as upfront medication and in combination with chemotherapy.