PT  - JOURNAL ARTICLE
AU  - SCHALLIER, DENIS
AU  - BERENDES, BEREND-JAN
AU  - LEFESVRE, PIERRE
AU  - EVERAERT, HENDRIK
TI  - Effective Treatment of Pleural Epitheloid Hemangio-endothelioma with Pazopanib: A Case Report
DP  - 2016 Jan 01
TA  - Anticancer Research
PG  - 351--354
VI  - 36
IP  - 1
4099  - http://ar.iiarjournals.org/content/36/1/351.short
4100  - http://ar.iiarjournals.org/content/36/1/351.full
SO  - Anticancer Res2016 Jan 01; 36
AB  - A patient with a pleural epitheloid hemangio-endothelioma (EHE) who failed to respond to six cycles of initial chemotherapy with iphosphamide and epirubicine was treated with pazopanib in second-line. A significant subjective and objective metabolic response on 18F-fluoro-deoxyglucose positron-emission tomography-computed tomography was noted. Based on this observation, the role of vasculoendothelial growth factor receptor inhibitors such as pazopanib (or other tyrosine kinase inhibitors), in the treatment of pleural EHE should be established through prospective collaborative studies as upfront medication and in combination with chemotherapy.