RT Journal Article SR Electronic T1 Clinicopathological Features of Surgically-resected Biliary Tract Cancer Following Chemo-radiation Therapy JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 335 OP 342 VO 36 IS 1 A1 SHOGO KOBAYASHI A1 KUNIHITO GOTOH A1 HIDENORI TAKAHASHI A1 HIROFUMI AKITA A1 SHIGERU MARUBASHI A1 TERUMASA YAMADA A1 TERUKI TESHIMA A1 KINJI NISHIYAMA A1 MASAHIKO YANO A1 HIROAKI OHIGASHI A1 OSAMU ISHIKAWA A1 MASATO SAKON YR 2016 UL http://ar.iiarjournals.org/content/36/1/335.abstract AB Aim: We retrospectively investigated surgery following chemo-radiation in patients with biliary tract cancer (BTC) treated at our Institution. Patients and Methods: Among 339 patients, 44 patients underwent chemo-radiation prior to surgery. Chemo-radiation entailed 2-3 months of standardized chemotherapy and 50-60 Gy radiation at the main tumor and regional and para-aortic lymph nodes. Results: Thirty-one BTC cases were classified as initially resectable (IR) and 13 as initially un-resectable (UR). Eighty percent of the BTCs were diagnosed as extrahepatic bile duct cancers. Gemcitabine (1,000 mg/m2) and radiation was used to treat 59% of patients. Thirty percent of patients underwent hemi-hepatectomy, and 50% underwent pancreatoduodenectomy. The R0 resection rate was 90% among IR and 54% among UR, and 3-year survival rates were 82% for IR and 17% for UR, respectively. Conclusion: This retrospective analysis suggests that surgery after chemoradiation may contribute to R0 resection rate and survival for initially resectable BTC.