PT  - JOURNAL ARTICLE
AU  - HENKENBERENS, CHRISTOPH
AU  - TOKLU, HAKAN
AU  - TAMME, CARSTEN
AU  - BRUNS, FRANK
TI  - Clinical Value of Squamous Cell Carcinoma Antigen (SCCAg) in Anal Cancer – A Single-Center Retrospective Analysis
DP  - 2016 Jun 01
TA  - Anticancer Research
PG  - 3173--3177
VI  - 36
IP  - 6
4099  - http://ar.iiarjournals.org/content/36/6/3173.short
4100  - http://ar.iiarjournals.org/content/36/6/3173.full
SO  - Anticancer Res2016 Jun 01; 36
AB  - Aim: To assess the clinical value of squamous cell carcinoma antigen (SCCAg) in anal cancer for chemoradiotherapy (CRT) patients. Patients and Methods: In 24 patients with SCC of the anus, SCCAg was determined before CRT and at every follow-up visit. Results: 16/24 (66.7%) had normal SCCAg and 11/16 (68.8%) achieved complete remission (CR), while 7/8 (87.5%) with elevated SCCAg achieved CR. In two patients, elevated SCCAg was observed after radiotherapy. One was false-positive and one was true-positive leading to diagnosis of metachronous recurrent and metastatic disease after interim CR. Conclusion: SCCAg was inappropriate to predict the clinical outcome but can provide additional information on the regular follow-up examinations to detect a relapse.